Author: envgencauses

Chapter 16. Toward a Multidimensional Matrix Risk Model for Autism

Abraham A, et al., 2008. Minds, persons and space: an fMRI investigation into the relational complexity of higher-order intentionality. Conscious Cogn. 17(2):438-50. doi: 10.1016/j.concog.2008.03.011.

Belgard TG et al., 2014. Population structure confounds autism genetic classifier. Mol Psychiatry. 19(4):405-7. doi: 10.1038/mp.2013.34.

Felleman DJ and Van Essen DC. 1991. Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex. 1(1):1-47.

Gergely, G. and JS Watson. 1999. Contingency perception and the social-feedback model. in: Philippe Rochat, Ed. Early Social Cognition (Hillsdale, NJ: Erlbaum, 1999).

Kontaris et al., 2009. Dissociation of extrastriate body and biological-motion selective areas by manipulation of visual-motor congruency. Neuropsychologia. 47(14): 3118–3124. doi: 10.1016/j.neuropsychologia.2009.07.012.

Milne E et al., 2009. Independent component analysis reveals atypical electroencephalographic activity during visual perception in individuals with autism. Biol Psychiatry. 65(1):22-30. doi: 10.1016/j.biopsych.2008.07.017.

Mountcastle VB et al., 1997. The columnar organization of the neocortex. Brain. 1120 ( Pt 4):701-22.

Nevison CD. 2014. A comparison of temporal trends in United States autism prevalence to trends in suspected environmental factors. Environ Health. 13:73. doi: 10.1186/1476-069X-13-73.

Okamoto Y et al., 2014. Attenuation of the contingency detection effect in the extrastriate body area in autism spectrum disorder. Neurosci Res. 87:66-76. doi: 10.1016/j.neures.2014.06.012.

Robinson EB et al., 2014. Response to ‘Predicting the diagnosis of autism spectrum disorder using gene pathway analysis’. Mol Psychiatry19(8):859-61. doi: 10.1038/mp.2013.125.

Skafidas E et al., 2014. Response to Belgard et al. Mol Psychiatry. 19(4):407-9. doi: 10.1038/mp.2013.186.

Skafidas E et al., 2014. Predicting the diagnosis of autism spectrum disorder using gene pathway analysis. Mol Psychiatry. 19(4):504-10. doi: 10.1038/mp.2012.126.

Schroeder JC et al., 2015. Genetic animal models for autism spectrum disorder. Curr Top Behav Neurosci. 2015 Nov 25 pp 1-14.

Talkvik I et al., 2015. Clinical Phenotype of De Novo GNAO1 Mutation. Child Neurology, 2:2 doi: 10.1177/2329048X15583717

Theoharides TC et al., 2013. Focal brain inflammation and autism. J Neuroinflammation. 10:46. doi: 10.1186/1742-2094-10-46.

Uddin M et al., 2014. Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder. Nat Genet. 46(7):742-7. doi: 10.1038/ng.2980.

Veenstra-VanderWeele J, Blakely RD, 2012. Networking in autism: leveraging genetic, biomarker and model system findings in the search for new treatments. Neuropsychopharmacology. 37(1):196-212. doi: 10.1038/npp.2011.185.

Weiner et al., 2011. Not one extrastriate body area: Using anatomical landmarks, hMT+ and visual field maps to parcellate limb-selective activations in human lateral occipitotemporal cortex. Neuroimage. 56(4): 2183–2199. doi: 10.1016/j.neuroimage.2011.03.041

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Chapter 14. Study Designs for Meaningful Future Causal Research in Autism

Barr, K. 2015. Vaccine Whistleblower: Exposing Autism Research Fraud in the CDC. Skyhorse Publishing, New York.

Curtis B, et al., 2015. Examination of the safety of pediatric vaccine schedules in a non-human primate model: assessments of neurodevelopment, learning and social behavior. Environ Health Perspect. 123(6):579-89. doi: 10.1289/ehp.1408257.

Fine PE and RT Chen. 1992. Confounding in studies of adverse reactions to vaccines. Am J Epidemiol. 136(2):121-35.

Gadad BS et al., 2015. Administration of Thimerosal-containing vaccines to infant rhesus macaques does not result in autism-like behavior or neuropathology. Proc Natl Acad Sci U S A. 112(40):12498-503. doi: 10.1073/pnas.1500968112.

Han S et al. 2012. Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission. Nature. 489(7416):385-90. doi: 10.1038/nature11356.

VaccinePapers.org. 2015. Gadad et al. 2015 PNAS Journal. Vaccine Papers: An Objective Look at Vaccines Dangers, Oct 27, 2015. http://vaccinepapers.org/gadad-et-al-2015-pnas-journal/

Sebro R and JJ Rogus. 2010. The power of the Transmission Disequilibrium Test in the presence of population stratification. Eur J Hum Genet. 18(9):1032-8. doi: 10.1038/ejhg.2010.57.

SafeMinds, 2016 (accessed 1/5/2016). Vaccines and Autism: What do Epidemiological Studies Really Tell Us? www.safeminds.org/wp-content/uploads/2013/04/SafeMinds-Epidemiological-Rebuttal.pdf

Verstraeten, T., R. David and F. DeStefano. 2000. Thimerosal VSD Study Phase I. CDC Internal Report Feb 29, 2000 marked “CONFIDENTIAL” and “DO NOT COPY OR RELEASE”. http://www.autismhelpforyou.com/EXPERT%20PAPER%20-%20Thimerosal%20VSD%20study001%20-%20Internet%20File.pdf Accessed Jan 6, 2016

Wahlund, S. 1928. Zusammensetzung von Population und Korrelationserscheinung vom Standpunkt der Vererbungslehre aus betrachtet. Hereditas 11:65–106.

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Chapter 13. Concepts of Comorbidity in Autism and Autism Research

Abbeduto, L. et al., 2015. Chapter 8. Neurodevelopmental Disorders, The American Psychiatric Publishing Textbook of Psychiatry (6 ed.). Arlington, VA: American Psychiatric Publishing. ISBN 978-1-58562-444-7.

Amiet C, et al., 2013. Epilepsy in simplex autism pedigrees is much lower than the rate in multiplex autism pedigrees. Biol Psychiatry. 74(3):e3-4. doi: 10.1016/j.biopsych.2013.01.037.

Bilder DA, 2016. Brief Report: the prevalence of Neurofibromatosis Type 1 among children with autism spectrum disorder identified by the autism and developmental disabilities monitoring network. J Autism Dev Disord. 2016 Jul 27.

Bird G, R Cook. 2013. Mixed emotions: the contribution of alexithymia to the emotional symptoms of autism. Transl Psychiatry3:e285. doi: 10.1038/tp.2013.61.

Cook R et al. 2013. Alexithymia, not autism, predicts poor recognition of emotional facial expressions. Psychol Sci. 24(5):723-32. doi: 10.1177/0956797612463582.

Crespi, B et al. 2010. Comparative genomics of autism and schizophrenia. PNAS 107:1736-1741.

Frye RE and DA Rossignol. 2016. Identification and treatment of pathophysiological comorbidities of autism spectrum disorder to achieve optimal outcomes. Clin Med Insights Pediatr. 2016 Jun 15;10:43-56. doi: 10.4137/CMPed.S38337. eCollection 2016.

Griffin C et al., 2015. Alexithymia in children with and without autism spectrum disorders. Autism Res. doi: 10.1002/aur.1569.

La Malfa G et al. 2004. Autism and intellectual disability: a study of prevalence on a sample of the Italian population. J Intellect Disabil Res. 48:262–7.

LaFrance Jr WC et al., 2008. Psychiatric comorbidities in epilepsy. Int Rev Neurobiol. 83:347–83.

Iverson JM and RH Wozniak. 2007. Variation in vocal-motor development in infant siblings of children with autism. J Autism Dev Disord. 37(1):158-70.

Silani, G et al.2007. Levels of emotional awareness and autism: An fMRI study. Social Neuroscience 3:97-112.

Tuchman R et al.. 2002. Epilepsy in autism. Lancet Neurol 1: 352–358.

Wang Q et al., 2015. Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS. Hum Genet.134(11-12):1195-209. doi: 10.1007/s00439-015-1596-8.

Zerbo O. 2015. Immune mediated conditions in autism spectrum disorders. Brain Behav Immun. 46:232-6. doi: 10.1016/j.bbi.2015.02.001.

Zerbo O et al. 2016. Maternal mid-pregnancy C-reactive protein and risk of autism spectrum disorders: the early markers for autism study. Transl Psychiatry. 6:e783. doi: 10.1038/tp.2016.46.

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Chapter 12. Vaccine-Autism Studies Ignored by the CDC

Agmon-Levin N et al. 2009. Vaccines and autoimmunity. Nat Rev Rheumatol. 5:648–652.

Atkinson et al., 2002. General Recommendations on Immunization Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the American Academy of Family Physicians (AAFP) http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5102a1.htm

Blaurock-Busch E et al., 2012. Toxic metals and essential elements in hair and severity of symptoms among children with autism. Maedica 7(1):38-48.

Bradstreet, J. et al.,2003. A case-control study of mercury burden in children with autistic spectrum disorders. J. American Physicians and Surgeons. 8:76-79.

Deavenport-Saman A et al., 2015. Do children with autism overutilize the emergency department? examining visit urgency and subsequent hospital admissions. Matern Child Health J. 2015 Oct 31.

Delong G, 2011. A positive association found between autism prevalence and childhood vaccination uptake across the U.S. population. J Toxicol Environ Health A. 74(14):903-16. doi: 10.1080/15287394.2011.573736.

DeSoto MC. 2008. A reply to Soden et al.: your data shows autistic children have higher levels of heavy metals. Clin Toxicol (Phila). 46(10):1098; author reply 1098. doi: 10.1080/15563650802314368.

Fido A and S Al-Saad, 2005. Toxic trace elements in the hair of children with autism. Autism. 9(3):290-8.

Gallagher CM and MS Goodman. 2010. Hepatitis B vaccination of male neonates and autism diagnosis, NHIS 1997-2002. J Toxicol Environ Health A. 73(24):1665-77. doi: 10.1080/15287394.2010.519317.

Geier DA and MR Geier. 2007. A case series of children with apparent mercury toxic encephalopathies manifesting with clinical symptoms of regressive autistic disorders. J Toxicol Environ Health A. 70(10):837-51.

Hobson D. 1973. Postgrad Med J. 1973. The potential role of immunological adjuvants in influenza vaccines. 49(569):180-84.

Holmes AS et al. 2003. Reduced levels of mercury in first baby haircuts of autistic children. Int J Toxicol. 22(4):277-85.

Langer-Gould A et al. 2014. Vaccines and the risk of multiple sclerosis and other central nervous system demyelinating diseases. JAMA Neurol. 2014 Dec;71(12):1506-13. doi: 10.1001/jamaneurol.2014.2633.

Li X et al., 2009. Elevated immune response in the brain of autistic patients. J Neuroimmunol. 207(1-2):111-6. doi: 10.1016/j.jneuroim.2008.12.002.

Liu XQ, 2011. Identification of genetic loci underlying the phenotypic constructs of autism spectrum disorders. J Am Acad Child Adolesc Psychiatry. 50(7):687-696.e13. doi: 10.1016/j.jaac.2011.05.002.

McDonald K et al.,2008. Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma. J Allergy Clin Immunol. 121(3):626-31. doi: 10.1016/j.jaci.2007.11.034.

Mohamed Fel B et al., 2015. Assessment of hair aluminum, lead and mercury in a sample of autistic Egyptian children: environmental risk factors of heavy metals in autism. Behav Neurol. 2015:545674. doi: 10.1155/2015/545674.

Moise L et al., 2015. T cell epitope redundancy: cross-conservation of the TCR face between pathogens and self and its implications for vaccines and auto-immunity. Expert Rev Vaccines. 2015 Nov 20. DOI:10.1586/14760584.2016.1123098

Molina V and Y Shoenfeld. 2005. Infection, vaccines and other environmental triggers of autoimmunity. Autoimmunity. 38(3):235-45.

Nataf R et al., 2006. Porphyrinuria in childhood autistic disorder: implications for environmental toxicity. Toxicol Appl Pharmacol. 214(2):99-108.

National Academy of Sciences, 2012. Adverse effects of vaccines: evidence and causality. Committee to Review Adverse Effects of Vaccines; Institute of Medicine 978-0-309-21435-3 http://www.commed.vcu.edu/IntroPH/Communicable_Disease/2012/adverseffectsVaccines.pdf

Orbach, H. 2010. Vaccines and Autoimmune Diseases of the Adult. Discovery Medicine. http://www.discoverymedicine.com/Hedi-Orbach/2010/02/04/vaccines-and-autoimmune-diseases-of-the-adult/

Palmer RF et al., 2006. Environmental mercury release, special education rates and autism disorder: an ecological study of Texas. Health Place. 12(2):203-9.

Poling JS, et al., 2006. Developmental regression and mitochondrial dysfunction in a child with autism. J Child Neurol. 21(2):170-2.

Rinaldi M et al., 2014. Immune thrombocytopaenic purpura: an autoimmune cross-link between infections and vaccines. Lupus. 2014 May;23(6):554-67. doi: 10.1177/0961203313499959.

Rosenhall U et al., 1999. Autism and hearing loss. J Autism Dev Disord. 29(5):349-57.

Seneff S et al., 2012. Empirical data confirm autism symptoms related to aluminum and acetaminophen exposure. Entropy 14(11), 2227-2253; doi:10.3390/e14112227.

Sharpe MA, et al., 2013. B-Lymphocytes from a population of children with autism spectrum disorder and their unaffected siblings exhibit hypersensitivity to thimerosal.  J Toxicol. 2013:801517. doi: 10.1155/2013/801517.

Singh VK et al., 1998. Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism. Clin Immunol Immunopathol. 89(1):105-8.

Soden SE. 2007. 24-hour provoked urine excretion test for heavy metals in children with autism and typically developing controls, a pilot study. Clin Toxicol (Phila). 45(5):476-81.

Thomas P et al., 2012. The association of autism diagnosis with socioeconomic status. Autism. 2012 16(2):201-13. doi: 10.1177/1362361311413397.

Wahlund, S. 1928. Zusammensetzung von Population und Korrelationserscheinung vom Standpunkt der Vererbungslehre aus betrachtet. Hereditas 11:65–106.

Vargas DL et al., 2005. Neuroglial activation and neuroinflammation in the brain of patients with autism. Ann Neurol. 57(1):67-81.

Yasuda H and T Tsutsui. 2013. Assessment of infantile mineral imbalances in autism spectrum disorders (ASDs). Int J Environ Res Public Health. 10(11):6027-43. doi: 10.3390/ijerph10116027.

Yasuda H et al., 2013. Estimation of autistic children by metallomics analysis. Sci Rep. 3:1199. doi: 10.1038/srep01199.

Yirkud, YV, et al. 2009. Familial aggregation of quantitative autistic traits in multiplex versus simplex autism. Am J Med Genet B Neuropsychiatr Genet. 150B: 328–334.

Young HA et al., 2008. Thimerosal exposure in infants and neurodevelopmental disorders: an assessment of computerized medical records in the Vaccine Safety Datalink. J Neurol Sci. 271(1-2):110-8. doi: 10.1016/j.jns.2008.04.002.

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