Chapter 1. Background and Concepts 5
Chapter 2. Symptoms and Diagnosis of Autism 69
Chapter 3. Evidence of Genetic and Epigenetic Risk Components of Autism
and Autism Spectrum Disorder 87
Chapter 4. Speech, Language, and Communication Phenotypes in ASD 116
Chapter 5. Genetic and Environmental Factors That Influence
Social Cognitive Skills in ASD 134
Chapter 6. Cognitive Phenotypes in ASD 153
Chapter 7. Repetitive Motor Behaviors and Seizure Phenotypes 159
Chapter 8. Sensory Phenotypes and Sensory Processing Disorder 165
Chapter 9. Immunological Factors in Autism and ASD 169
Chapter 10. Gastrointestinal and Renal Phenotypes 192
Chapter 11. Neurotoxin-Induced Autoimmune-Mediated
Neurological Damage in Autism 200
Chapter 12. Vaccine-Autism Studies Ignored by the CDC 217
Chapter 13. Concepts of Comorbidity in Autism and Autism Research 230
Chapter 14. Study Designs for Meaningful Future Causal Research
in Autism 241
Chapter 15. Biological Pathways and Networks Views of Autism 253
Chapter 16. Toward a Multidimensional Matrix Risk Model
for Autism 260
Chapter 17. The Logic of Prevention in Autism
and Gene-Informed Treatment 271
Chapter 18. Injecting Objective Association and Causal Inference into
Clinical Trials, Prevention, Diagnosis, and Treatment of ASD 292
The Environmental and Genetic Causes of Autism Reference Resource 